REPRODUCIBLE ANIMAL-MODEL OF ACUTE BLEEDING ULCER - ULCER MAKER

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 71  (6) , 961-964
Abstract
An instrument was developed which created an experimental model of an acute bleeding gastric ulcer. The diameter and depth of these gastric ulcers were reproducible. The instrument was used endoscopically or at laparotomy. Using this ulcer model nonsurgical modalities for the treatment of upper gastrointestinal bleeding can be compared in a controlled manner. This standard experimental model may also facilitate comparison of results among different research groups. Acute studies were performed in dogs under general anesthesia.