THE MECHANISM OF THE ACTION OF DICARBOXYLIC ACIDS IN BLOOD COAGULATION
- 31 August 1940
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 130 (3) , 574-581
- https://doi.org/10.1152/ajplegacy.1940.130.3.574
Abstract
Dicarboxylic acids reduce coagulation time in vit. K deficient chicks but do not alter coagulation times in heparinized animals. Fluorides reduce coagulation times in normal animals. The action of fluorides and dicarboxylic acids is one detd. by the law of mass action involving directly Ca ion conc. and indirectly prothrombin conc. A Ca prothrombinate is hypothesized.This publication has 2 references indexed in Scilit:
- A Quantitative Biological Assay of Vitamin KJournal of Nutrition, 1939
- THE EFFECT OF CERTAIN SULFUR COMPOUNDS ON THE COAGULATION OF BLOODAmerican Journal of Physiology-Legacy Content, 1936