The organic chemistry of mechanism‐based enzyme inhibition: A chemical approach to drug design
- 1 July 1984
- journal article
- review article
- Published by Wiley in Medicinal Research Reviews
- Vol. 4 (3) , 415-447
- https://doi.org/10.1002/med.2610040305
Abstract
No abstract availableKeywords
This publication has 97 references indexed in Scilit:
- Enzyme-activated irreversible inhibition of rat and mouse brain 4-aminobutyric acid-α-ketoglutarate transaminase by 5-fluoro-4-oxo-pentanoic acidBiochemical and Biophysical Research Communications, 1982
- The time-dependent inactivation of aromatase by 17β-hydroxy-10-methylthioestra-1,4-dien-3-oneBiochemical and Biophysical Research Communications, 1981
- N-(1-Methyl)cyclopropylbenzylamine: A novel inactivator of mitochondrial monoamine oxidaseBiochemical and Biophysical Research Communications, 1981
- Inactivation of λ‐cystathionase by λ‐fluorinated amino acidsFEBS Letters, 1981
- Inactivation of pyridoxal 5'‐phosphate‐dependent enzymes by 5‐nitro‐L‐norvaline, an analog of L‐glutamateFEBS Letters, 1981
- Irreversible inactivation of the flavoenzyme alcohol oxidase with acetylenic alcoholsBiochemical and Biophysical Research Communications, 1980
- Mechanism-based inhibitors of elastaseBiochemical and Biophysical Research Communications, 1980
- Inhibition of testosterone 5α-reductase by a proposed enzyme-activated, active site-directed inhibitorBiochemical and Biophysical Research Communications, 1980
- CIDNP evidence for electron transfer between two neutral radicals in solutionJournal of the American Chemical Society, 1978
- Fluorinated pyrimidines. Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotidesBiochemistry, 1974