Tricyclic dose requirements across pregnancy
- 1 October 1993
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 150 (10) , 1541-1542
- https://doi.org/10.1176/ajp.150.10.1541
Abstract
In a series of eight pregnant women, the authors found that the doses of tricyclic antidepressants required to achieve remission of symptoms and adequate serum levels increased during the second half of pregnancy. During the final trimester, the mean dose required was 1.6 times the mean dose required when the patients were not pregnant.Keywords
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