Induction of an Interleukin-1 Receptor Antagonist-like Component Produced from Mouse Spleen Cells by Bovineκ-Caseinoglycopeptide
- 1 January 1995
- journal article
- Published by Taylor & Francis in Bioscience, Biotechnology, and Biochemistry
- Vol. 59 (6) , 1166-1168
- https://doi.org/10.1271/bbb.59.1166
Abstract
Bovine kappa-caseinoglycopeptide (residues 106-169, CGP) bound to mouse plastic-adherent cells. A culture supernatant prepared from mouse spleen cells and plastic-adherent cells cultured with CGP significantly inhibited the lipopolysaccharide-induced proliferative response of mouse spleen lymphocytes. The inhibition of proliferation by the culture supernatant was completely overcome by the addition of the anti-interleukin-1 receptor antagonist antibody.Keywords
This publication has 0 references indexed in Scilit: