Pharmacological Investigation of the Nature of the Innervation of the Muscles of Helix Aspersa

Abstract
The isolated columellar muscle of Helix aspersa is caused to contract by addition to it of ephedrine, adrenaline, veratrine, Ba++ and acetylcholine. Adrenaline and acetylcholine are active in concentrations of 10-6 or less. The action of acetylcholine is potentiated by eserine and abolished by atropine, but not by curare, indicating a muscarinic cholinergic innervation of this muscle. The heart muscle is sensitive to sympathornimetic substances only. The muscle of the alimentary canal is insensitive to drugs.

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