Treatment of TRIC infection of the eye with rifampicin or chloramphenicol.

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Abstract
An open trial was carried out on 63 patients in London, England to assess the efficacy of 1% rifampicin eye ointment in comparison with 1% chloramphenicol eye ointment in the treatment of sexually transmitted TRIC [trachoma inclusion conjunctivitis] infection of the eye. Patients included were selected on the basis of positive cultures for Chlamydia trachomatis. Three wk treatment with rifampicin eye ointment used 3 times daily was not sufficient to cure the disease, but a 6 or 7 wk course gave 90% clinical and microbiological cure rate. Treatment with chloramphenicol eye ointment 3 times daily for 4 to 6 wk failed to cure the disease.