THE EFFECTS OF WATER DIURESIS AND EXERCISE ON THE VOLUME AND COMPOSITION OF THE URINE

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Abstract
Results are presented of expts. carried out over 3 yrs. on the changes occurring during diuresis and the effects of exercise, time of day, and meals on these changes. As a result of exercise, water diuresis may or may not be inhibited. pH of the urine during diuresis tends towards 6.9 irrespective of initial level; during exercise there was always a marked fall. There is always a fall in plasma flow, in filtration rate and a rise in filtration fraction during exercise. As a consequence of taking water, there is either a rise or fall in chloride excretion. This is a reflection of the varying degrees of tubular activity towards chloride and, as a result of exercise, tubular activity increases still further and there is a marked fall of chloride excretion. The findings offer support for the postulate and there is a proximal and distal component to reab-sorption.