Extraneural Pathologic Prion Protein in Sporadic Creutzfeldt–Jakob Disease
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Open Access
- 6 November 2003
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 349 (19) , 1812-1820
- https://doi.org/10.1056/nejmoa030351
Abstract
In patients with sporadic Creutzfeldt–Jakob disease, pathologic disease-associated prion protein (PrPSc) has been identified only in the central nervous system and olfactory-nerve tissue. Understanding the distribution of PrPSc in Creutzfeldt–Jakob disease is important for classification and diagnosis and perhaps even for prevention.Keywords
This publication has 30 references indexed in Scilit:
- Cannibals and garbage pilesNature, 2003
- Irregular presence of abnormal prion protein in appendix in variant Creutzfeldt-Jakob diseaseJournal of Neurology, Neurosurgery & Psychiatry, 2002
- Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjectsAnnals of Neurology, 1999
- Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samplesThe Lancet, 1999
- Molecular analysis of prion strain variation and the aetiology of 'new variant' CJDNature, 1996
- Molecular basis of phenotypic variability in sporadc creudeldt‐jakob diseaseAnnals of Neurology, 1996
- A new variant of Creutzfeldt-Jakob disease in the UKPublished by Elsevier ,1996
- Human spongiform encephalopathy: The national institutes of health series of 300 cases of experimentally transmitted diseaseAnnals of Neurology, 1994
- Prion protein is abnormally accumulated in inclusion-body myositisNeuroReport, 1993
- Scrapie prions aggregate to form amyloid-like birefringent rodsCell, 1983