Fecal Bacterial β-Glucuronidase: Control by Diet
- 1 February 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 183 (4123) , 416-417
- https://doi.org/10.1126/science.183.4123.416
Abstract
The effect of a mixed Western, high meat diet or a nonmeat diet on the intestinal bacterial β-glucuronidase activity was studied in human volunteers. This enzyme was significantly higher in stools of subjects on a high meat diet as compared to the nonmeat regimen. Thus, intestinal flora of subjects on a high meat diet was more able to hydrolyze glucuronide conjugates than that of individuals on a nonmeat diet. This, in turn, may raise the amount of substances, such as carcinogens, within the colonic lumen.Keywords
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