The Association Between Parental Occupation and Childhood Malignancy

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Abstract
A case control study was conducted to test Fabia and Thuys observation that there was an excess of fathers in hydrocarbon-related occupations among children who died of childhood cancer compared to controls. The study comprised 692 children who were born and died in Massachusetts [USA] for 1947-1957 and 1963-1967 and a control group of 1384. No significant association was found between the 4 major groups of childhood cancer and the 3 hydrocarbon-related occupations: mechanics and gas station attendants, machinists and painters, cleaners and dyers. There were 2 significant association: paternal employment as a paper or pulp mill worker was associated with tumors of brain and other parts of nervous system (relative odds of 2.8); and paternal employment as a mechanic or machinist was associated with tumors of urinary tract (relative odds of 2.5). A weak association between childhood leukemia-lymphoma and parent age was observed.

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