Mutagenesis by Photoactivation of Chlorpromazine, a Tranquilizer of the Phenothiazine Group

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Abstract
The tranquilizer chlorpromazine, in combination with visible light or near-u.v. radiation, can cause base-pair substitution mutations and frameshift mutations in Salmonella typhimurium. The mutagenic damage is subject to repair by the bacterial excision~repair system.

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