Passive Avoidance Behavior in Mice: Interaction Between Age and Genotype

Abstract
BALB/c (BALB) and C57BL/6 (C57) mice were tested in a passive avoidance apparatus at different ages (6, 12 and 24 months). Results showed a clear-cut retention decrease only in 24 month old BALB mice in comparison with younger animals. No significant age effect was evident in C57 mice.