Population data on benign and severe forms of X-linked muscular dystrophy
- 1 March 1987
- journal article
- conference paper
- Published by Springer Nature in Human Genetics
- Vol. 75 (3) , 217-220
- https://doi.org/10.1007/bf00281062
Abstract
Epidemiological data on Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD) from a large sample of the Italian population are reported. For BMD the incidence rate was found to be 5.5x10-5 liveborn males (lbm) and the prevalence rate, 13.1x10-6; the mutation rate was estimated to be about 6.0x10-6. For DMD the incidence and prevalence rates were found to be respectively 26x10-5 lbm and 31.6x10-6. The DMD mutation rate obtained by the Haldane formula was 86.6x10-6 and by the semi-direct method, 65.6x10-6. The results are discussed in the light of possible allelism of BMD and DMD.This publication has 16 references indexed in Scilit:
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