Structure‐Activity Relationship Studies of CNS Agents, Part 32[1]: Effect of Structural Modifications in 1‐Arylpiperazine Derivatives on α1‐Adrenoreceptor Affinity
- 1 January 1997
- journal article
- research article
- Published by Wiley in Archiv der Pharmazie
- Vol. 330 (6) , 177-180
- https://doi.org/10.1002/ardp.19973300605
Abstract
The α1-adrenergic and 5-HT1A serotonergic receptor affinities of a series of 1-arylpiperazines are presented. The role of the spacer and the influence of the terminal substituents on the α1-adrenoreceptor affinity and the 5-HT1A/α1 receptor selectivity are discussed.Keywords
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