Comparative analysis of cell distribution in the pigment epithelium and the visual cell layer of chimaeric mice
Open Access
- 1 October 1976
- journal article
- research article
- Published by The Company of Biologists in Development
- Vol. 36 (2) , 425-430
- https://doi.org/10.1242/dev.36.2.425
Abstract
In chimaeras of both rdrdCC⟷++cc and rdrdcc⟷ + +CC combinations two types of distribution were observed. In a majority of the chimaeras both retinal layers were chimaeric; whereas in a few cases the pigment epithelium was chimaeric but the visual cell layer was made of + + cells only. No spatial relation was observed in the distribution of the cells in the two layers. The two eyes of the individuals were nearly always identical with regard to occurrence of chimaerism in the two layers. The findings are discussed in the light of the possible site and mode of expression of the rd gene.This publication has 6 references indexed in Scilit:
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