Pathways of glucose metabolism in the isolated islet of the goosefish in vitro

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Abstract
The contribution of the pentose cycle to the oxidation of glucose by goosefish islet has been estimated in vitro using 2 different procedures. The first procedure is based on the total amount of glucose utilized and the yields of C14O2 from glucose -1-C14 and -6-C14. The second is based on the amount of randomizazation of carbon 2 of glucose-2-Cl4 during its conversion into the glucose unit of glycogen. At the normal blood glucose concentration of the goosefish (25 mg/100 ml) the fraction of glucose metabolized via the pentose cycle was less than 0.11. This fraction decreased when the glucose concentration was increased to 200 mg/100 ml.

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