Effect of Ezetimibe and/or Simvastatin on Coenzyme Q10 Levels in Plasma
- 1 January 2006
- journal article
- research article
- Published by Springer Nature in Drug Safety
- Vol. 29 (8) , 703-712
- https://doi.org/10.2165/00002018-200629080-00007
Abstract
Background:HMG-CoA reductase inhibitors (‘statins’) have been associated with a decrease in ubidecarenone (ubiquinone) levels, a lipophilic enzyme also known as coenzyme Q10 (CoQ10), due to...Keywords
This publication has 32 references indexed in Scilit:
- The Effect of HMG-CoA Reductase Inhibitors on Coenzyme Q10Drug Safety, 2005
- Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunctionThe American Journal of Cardiology, 2004
- Atorvastatin Decreases the Coenzyme Q10 Level in the Blood of Patients at Risk for Cardiovascular Disease and StrokeArchives of Neurology, 2004
- Inhibition of Intestinal Cholesterol Absorption by Ezetimibe in HumansCirculation, 2002
- Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitorsMolecular Aspects of Medicine, 1997
- Lipid‐lowering drugs and mitochondrial function: effects of HMG‐CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratioBritish Journal of Clinical Pharmacology, 1996
- Effects of clofibrate, phthalates and probucol on ubiquinone levelsChemico-Biological Interactions, 1994
- Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin.Journal of Clinical Pathology, 1993
- The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranesChemico-Biological Interactions, 1990
- Effects of an Inhibitor of 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase on Serum Lipoproteins and Ubiquinone-10 Levels in Patients with Familial HypercholesterolemiaNew England Journal of Medicine, 1981