Spironolactone and Its Main Metabolite, Canrenoic Acid, Block Human Ether-a-Go-Go–Related Gene Channels
- 18 February 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 107 (6) , 889-895
- https://doi.org/10.1161/01.cir.0000048189.58449.f7
Abstract
Background— It has been demonstrated that spironolactone (SP) decreases the QT dispersion in chronic heart failure. In this study, the effects of SP and its metabolite, canrenoic acid (CA), on huma...Keywords
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