Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G+C-content biases.
Open Access
- 1 July 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in Molecular Biology and Evolution
- Vol. 9 (4) , 678-687
- https://doi.org/10.1093/oxfordjournals.molbev.a040752
Abstract
A simple mathematical method is developed to estimate the number of nucleotide substitutions per site between two DNA sequences, by extending Kimura's (1980) two-parameter method to the case where a G+C-content bias exists. This method will be useful when there are strong transition-transversion and G+C-content biases, as in the case of Drosophila mitochondrial DNA.Keywords
This publication has 0 references indexed in Scilit: