NUTRITIONAL DERMATOSES IN THE RAT

Publisher Website
Google Scholar
Abstract
When young rats are fed an otherwise adequate diet which contains insufficient magnesium there develops a disease characterized by hyperexcitability, tonic-clonic convulsive seizures, nephritis, hepatitis, vasodilatation, intense generalized erythema, edema of the skin, erythema multiforme, dermatitis, ulcers, hyperflexibility and hyperextensibility of the joints, edema of the dependent parts and finally nutritive failure and death.1Magnesium deficiency in calves results in the deposition of calcium salts in the yellow elastic fibers of the endocardium, of the aorta, jugular vein and larger arteries, of the surfaces of the diaphragm and of the trabeculae of the spleen.2Clinicians generally have lacked interest in magnesium deficiency and have neglected to explore the possibilities of its clinical significance. The clinical implications suggested by the experimental syndrome include tetany,1epilepsy,3arteriosclerosis,2nephrosis4and disseminated neurodermatitis.5In this communication disseminated neurodermatitis is compared with

This publication has 2 references indexed in Scilit: