Synthesis of the taxane ring system using an intramolecular Diels–Alder reaction of a 2-substituted diene
- 1 January 1986
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 7,p. 1303-1309
- https://doi.org/10.1039/p19860001303
Abstract
A synthesis of (1R/S,3R/S,8S/R)-8-methyltricyclo[9.3.1.03,8]pentadec-11-en-2-one, which is the ring system of the taxane natural products and contains 3 chiral centres having the required relative configuration, is described.This publication has 1 reference indexed in Scilit:
- Cephalomannine; a new antitumour alkaloid from Cephalotaxus manniiJournal of the Chemical Society, Chemical Communications, 1979