Visual Evoked Responses in the Brain Injured Monkey

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Abstract
PATHOLOGIC lesions of sufficient severity to give rise to homonymous hemianopic defects in man usually show decreased electric activity, particularly of the α-frequency waves over the involved cerebral hemisphere.1,2 The phenomenon of altered electric output is observed in both the spontaneous electroencephalogram and in summated evoked cortical responses.3-5 Both of these responses in man show striking variability in different individuals; the decreased electric output also appeared to be dependent on the duration of time from injury. It, therefore, seemed important to carry out a series of experiments in the primate visual system in which the location, extent, and durations of the injuries could be precisely controlled. This study addresses itself primarily to the evaluation of the summated visual evoked cortical responses, since the α-frequency or other rhythmic output of the monkey is not as well defined, or as well organized, as in man. Methods Twelve monkeys (Macacus

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