Lésions pulmonaires de la ventilation artificielle et de l’oxygénothérapie: étude expérimentale chez le chat

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Abstract
Groups of 6 cats were curarized and maintained under assisted ventilation with either air or a 35 % oxygen mixture. Lungs were then fixed and divided in small pieces, some of which were chosen at random for histological studies. Pulmonary lesions after assisted ventilation with air were rather discrete, even after 72 h. On the contrary, after the same period of ventilation with 35 % O2, all cats showed capillary dilatation, interstitial edema and intra-alveolar hemorrhagic exsudate.