The ultraviolet absorption of sheep thyroglobulin

Publisher Website
Google Scholar
Abstract
The absorption of thyroglobulin was detd. by means of a photographic method (mean error in detn. of K within 3%). 8 samples of sheep thyroglobulin (I.G. Farbenin-dustrie, 1 the A''s preparation), 1 sample of ox thyroglobulin (I.G. Farbenindustrie) were used. A successful analysis of the absorption curves was obtained only if both the acid and the alkaline absorption of the thyroglobulin were studied. This was done by introducing the so-called differential extinction coefficients, which were equal to the difference between the alkaline and the acid extinction coefficients. In this way the occurrence in thyroglobulin of the characteristic (I containing) groups of thyroxine and of di-iodotyrosine was proved. Half the I of the thyroglobulin molecule was attributed to thyroxine, the other half to diiodotyrosine.

This publication has 1 reference indexed in Scilit: