Displacement of Sugar Triflates with C-Nucleophiles: D-Glucopyranose and D-Ribofuranose Chain Extension and Functionalization
- 1 June 1994
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 24 (11) , 1519-1530
- https://doi.org/10.1080/00397919408010152
Abstract
Treatment of methyl 4-O-benzyl-2,3-di-O-methoxymethyl-6-O-1-6-O-trifluoromethanesulfonyl-α -D-glucopyranoside 1 or 3-O-benzyl-1,2-O-isopropylidene-5-O-trifluoromethenesulfonyl-α-D-ribofuranoside 2 with a variety of functionalized C-nucleophiles in THF/HMPA leads to the corresponding chain-extended sugars in very good to excellent yields.Keywords
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