Cephabacins, new cephem antibiotics of bacterial origin. II. Isolation and characterization.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (12) , 1536-1545
- https://doi.org/10.7164/antibiotics.37.1536
Abstract
Fifteen components of new antibiotics, cephabacins, were isolated from the culture filtrates of Lysobacter lactamgenus YK-90, Xanthomonas lactamgena YK-280 and X. lactamgena YK-278. They were purified by column chromatography using cation-exchange resins, activated C, high porous resins and cation-exchange Sephadex and by preparative reverse-phase high performance liquid chromatography. The basic, water-soluble antibiotics were characterized as having a cephem skeleton and oligopeptide(s) as a side chain constituent from their spectroscopic analyses and amino acid analyses.This publication has 6 references indexed in Scilit:
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