Early Bubble CPAP and Outcomes in ELBW Preterm Infants
- 1 April 2003
- journal article
- Published by Springer Nature in Journal of Perinatology
- Vol. 23 (3) , 195-199
- https://doi.org/10.1038/sj.jp.7210904
Abstract
To test whether the introduction of early bubble continuous positive airway pressure (CPAP) results in improved respiratory outcomes in extremely low birth-weight infants. Outcomes of all infants between 401 and 1000 g born in a level 3 neonatal intensive care units (NICU) between July 2000 and October 2001 (period 2) were compared using historical controls (period 1). Early bubble (CPAP) was prospectively introduced in the NICU during period 1. Univariate and adjusted comparisons were made across time periods. Delivery room intubations, days on mechanical ventilation and use of postnatal steroids decreased (p<0.001) in period 2, while mean days on CPAP, number of babies on CPAP at 24 hours (p<0.001) and mean weight at 36 weeks corrected gestation also increased (p<0.05) after introduction of early bubble CPAP. Early bubble CPAP reduced delivery room intubations, days on mechanical ventilation, postnatal steroid use and was associated with increased postnatal weight gain with no increased complications.Keywords
This publication has 20 references indexed in Scilit:
- Nasal continuous positive airway pressure immediately after extubation for preventing morbidity in preterm infantsCochrane Database of Systematic Reviews, 2003
- Early versus delayed initiation of continuous distending pressure for respiratory distress syndrome in preterm infantsCochrane Database of Systematic Reviews, 2002
- Continuous distending pressure for respiratory distress in preterm infantsPublished by Wiley ,2002
- Nasal continuous positive airway pressure and outcomes of preterm infantsJournal of Paediatrics and Child Health, 2001
- Do Clinical Markers of Barotrauma and Oxygen Toxicity Explain Interhospital Variation in Rates of Chronic Lung Disease?Pediatrics, 2000
- Delivery Room Management of Extremely Low Birth Weight Infants: Spontaneous Breathing or Intubation?Pediatrics, 1999
- National institute of child health and human development (NICHD)-sponsored perinatal research networksSeminars in Perinatology, 1995
- Early treatment with nasal‐CPAPActa Paediatrica, 1993
- Respiratory management for low-birth-weight infantsCritical Care Medicine, 1993
- Early treatment with nasal continuous positive airway pressure in very low‐birth‐weight infantsActa Paediatrica, 1993