SOME EFFECTS OF POSTIRRADIATION TREATMENT WITH METABOLIC INHIBITORS AND NUTRIENTS UPON ULTRAVIOLET IRRADIATED SPORES OFSTREPTOMYCEST12

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Abstract
The effects of postradiation treatment with metabolic inhibitors (arsenate, azide, and dinitrophenol) and various cell nutrients (N-sources and sugars) upon ultraviolet irradiated spores of Streptomyces T12 have been studied. Changes in the frequency of induced variants which were not accompanied by effects upon survival, and increases of survival which were not associated with a change in variant frequency were observed. The results obtained indicate that the biological effects of ultraviolet radiation can be modified by the postradiation metabolism of the cell.