Endurance exercise alters the contractile responsiveness of rat heart to extracellular Na+ and Ca2+
- 1 October 1998
- journal article
- research article
- Published by Wolters Kluwer Health in Medicine & Science in Sports & Exercise
- Vol. 30 (10) , 1502-1509
- https://doi.org/10.1097/00005768-199810000-00006
Abstract
Endurance exercise alters the contractile responsiveness of rat heart to extracellular Na+ and Ca2+. Med. Sci. Sports Exerc., Vol. 30, No. 10, pp. 1502-1509, 1998. The isovolumic contractile responsiveness of left ventricular (LV) myocardium to altered extracellular [Ca2+], [Na+], and pacing frequency was examined using perfused hearts (37°C) isolated from sedentary (SED) and treadmill-trained (TR) adult female rats. The suppressive effect of reducing perfusate free [Ca2+] to 0.7 mM on LV developed pressure (ΔLVP) was greater in the TR hearts compared with SED hearts (P + Training elicited a small but significant (P 2+Keywords
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