Public Health Burden of Cancer in Ataxia-Telangiectasia Heterozygotes
Open Access
- 17 January 2001
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 93 (2) , 84-85
- https://doi.org/10.1093/jnci/93.2.84
Abstract
Knowing that mutations of a specific gene predispose to certain cancers is an important step toward more effective preventive or therapeutic measures for those cancers. The history of ataxia-telangiectasia (A-T) research illustrates how advances in genetic and molecular genetic technology are clarifying and quantifying the role of mutations at this genetic locus in common diseases and mortality in the general population.Keywords
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