2-Formyl derivatives of 6-methylergoline-I

1 January 1982

journal article
Published by Institute of Organic Chemistry & Biochemistry in Collection of Czechoslovak Chemical Communications

Vol. 47 (4) , 1235-1239
https://doi.org/10.1135/cccc19821235

Abstract

Reaction of ergoline derivatives I, III - VI with 2-alkoxy-1,3-dithiolan, generated in situ, gave the 2-(1,3-dithiolan-2-yl) derivatives VII, XI - XIV.Hydrolysis of the thioacetal group in these compounds produced 2-formylergoline derivatives, XV-XIX, which proved to have only a weak inhibitory effect on the secretion of prolactin.

Keywords

DITHIOLAN
XV XIX
DERIVATIVES VII
XIV.HYDROLYSIS
THIOACETAL GROUP
WEAK INHIBITORY
FORMYLERGOLINE DERIVATIVES

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