Proton magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy
- 1 February 1995
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 37 (2) , 279-281
- https://doi.org/10.1002/ana.410370222
Abstract
Proton magnetic resonance spectroscopic imaging (1H MRSI) has demonstrated decreased N‐acetyl compounds (NA) in the epileptogenic hippocampus in patients with temporal lobe epilepsy. We studied 8 patients with frontal lobe epilepsy and found mean NA/creatine (Cr) in the epileptogenic frontal lobe decreased by 27% compared with that of the contralateral homologous region (1.81 ±0.36 vs 2.49 ± 0.60, p < 0.008). In every patient, NA/Cr was decreased in the epileptogenic region by at least 5%. These findings suggest that 1H MRSI may be useful in the presurgical evaluation of patients with frontal lobe epilepsy.Keywords
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