MEDICAL AND PSYCHIATRIC COMPLICATIONS OF PENTAZOCINE AND TRIPELENNAMINE ABUSE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 41  (8) , 275-278
Abstract
The change in illicit drug use from 1973-1979 was studied in Chicago [Illinois, USA] veterans. Barbiturate and amphetamine use has decreased significantly. Nearly a 7-fold increase in pentazocine use has occurred. All but 1 of the pentazocine users added tripelennamine to the i.v. or s.c. injections. Instances [64] of medical or psychiatric complications including seizures, abscesses, depression and psychosis occurred in the 69 pentazocine and tripelennamine users. A possible pharmacologic explanation of the seizures and psychiatric complications is advanced. Most users of pentazocine and tripelennamine started in an attempt to withdraw from heroin or because of the poor quality of heroin available.

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