Integrated Screening for Down's Syndrome
Open Access
- 16 December 1999
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 341 (25) , 1935-1937
- https://doi.org/10.1056/nejm199912163412513
Abstract
Wald et al. (Aug. 12 issue)1 describe a protocol for screening for Down's syndrome that is based on tests performed during both the first and second trimesters of pregnancy. However, their estimates are based on data from multiple studies, some rather small. Most important, they fail to consider the advantages of a diagnosis in the first trimester.Keywords
This publication has 13 references indexed in Scilit:
- First trimester screening for aneuploidy: Serum biochemical markersSeminars in Perinatology, 1999
- First trimester screening for aneuploidy: Nuchal translucency sonographySeminars in Perinatology, 1999
- Prenatal Screening for Down's Syndrome — A Search for the Family's ValuesNew England Journal of Medicine, 1999
- Integrated Screening for Down's Syndrome Based on Tests Performed during the First and Second TrimestersNew England Journal of Medicine, 1999
- A screening program for trisomy 21 at 10–14 weeks using fetal nuchal translucency, maternal serum free β‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐AUltrasound in Obstetrics & Gynecology, 1999
- Letter. Correct estimation of parameters for ultrasound nuchal translucency screeningPrenatal Diagnosis, 1998
- Letter. Response to: Wald, N.J. and Hackshaw, A.K. (1997). Combining ultrasound and biochemistry in first‐trimester screening for Down's syndrome, Prenat. Diagn. , 17 , 821–829Prenatal Diagnosis, 1998
- Authors' replyPrenatal Diagnosis, 1998
- Combining Ultrasound and Biochemistry in First-Trimester Screening for Down's syndromePrenatal Diagnosis, 1997
- The Safety and Efficacy of Chorionic Villus Sampling for Early Prenatal Diagnosis of Cytogenetic AbnormalitiesNew England Journal of Medicine, 1989