Decrease of Ultraviolet-Induced DNA Injury in Human Skin by p-Aminobenzoic Acid Esters
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Dermatology
- Vol. 179 (4) , 196-199
- https://doi.org/10.1159/000248359
Abstract
The effect of a sunscreen containing a p-aminobenzoic acid (PABA) ester on ultraviolet-induced DNA injury was assessed on human epidermal cells by the measure of unscheduled DNA synthesis intensity. Our results show that DNA repair was reduced by approximately 50%. Therefore sunscreens based on PABA esters might be expected to reduce photocarcinogenesis.Keywords
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