A male-specific DNA probe detects heterochromatin sequences in a familial Yq- chromosome.

  • 1 November 1984
    • journal article
    • Vol. 36  (6) , 1394-6
Abstract
Using a recombinant DNA probe, we have demonstrated the presence of residual 3.4-kilobase (kb) repeat sequences in a family with a Yq- chromosome. The heterochromatin of this Y variant was not readily detectable with conventional chromosome-banding techniques. These data suggest that the breakpoint of the deletion occurs at the heterochromatin region proximal to the euchromatin/heterochromatin junction.