BIOLOGIC AND BIOCHEMICAL ACTIVITIES OF CORD FACTOR - WITH SPECIAL REFERENCE TO ITS ROLE IN THE VIRULENCE OF TUBERCLE BACILLI
- 1 January 1958
- journal article
- research article
- Published by Elsevier
- Vol. 77 (3) , 482-491
- https://doi.org/10.1164/artpd.1958.77.3.482
Abstract
Using the homogenate technique of whole body of mice, it was found that "cord factor" did not influence the survival and multiplication of either virulent or avirulent human tubercle bacilli in mouse bodies. The "cord factor" was toxic for mice, and caused a significant decrease in the activity of the succinic and malic dehydrogenase systems of the liver of mice.Keywords
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