Multiple Osteolysis of Peripheral Extremities in a Patient with Adult T Cell Leukemia/Lymphoma.
- 1 January 1999
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 38 (10) , 820-823
- https://doi.org/10.2169/internalmedicine.38.820
Abstract
A 67-year-old woman with severe pain in the peripheral extremities was admitted to our hospital. Radiography of the peripheral extremities revealed multiple osteolytic lesions. Antibody to human T cell leukemia virus type-I (HTLV-I) was positive, and right radial bone biopsy showed infiltration of adult T cell leukemic (ATL) cells. Irradiation therapy was effective in the osteolytic lesions. In the present case, elevation of IL-6 was detected, suggesting that IL-6 produced by ATL cells is related to their proliferation in the bone, and local osteolysis.Keywords
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