An in vitro model for drug absorption studies
- 1 June 1970
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 22 (6) , 423-426
- https://doi.org/10.1111/j.2042-7158.1970.tb08556.x
Abstract
The transfer of salicylic acid and of three sulphonamides from an aqueous phase of pH 2 or pH 5 through an intervening organic phase to an aqueous phase of pH 7.4 has been studied using a rotating cell. The manner of operation of the cell promotes rapid drug transfer without vortexing or emulsification of the phases. The rates of transfer of the drugs showed the anticipated pH dependance.Keywords
This publication has 3 references indexed in Scilit:
- An in vitro model for soluble drug absorptionJournal of Pharmacy and Pharmacology, 1967
- Drug Partitioning IIJournal of Pharmaceutical Sciences, 1964
- A NEW COUPLING COMPONENT FOR SULFANILAMIDE DETERMINATIONJournal of Biological Chemistry, 1939