Platelet storage pool disease in hybrid rats
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Heredity
- Vol. 75 (1) , 15-18
- https://doi.org/10.1093/oxfordjournals.jhered.a109855
Abstract
Fawn-hooded rats have a hemorrhagic disorder known as platelet storage pool deficiency. Parent stocks of Fawn-hooded, Long-Evans, and Wistar (DAB) rats and the progeny of their reciprocal crosses were studied for coat color and percentage 14C-Serotonin uptake and secretion by blood platelets. Progeny of Fawn-hooded and Wistar reciprocal crosses were dark- or light-hooded, whereas all reciprocal crosses with the Long-Evans stock were dark-hooded. The light or fawn hood was significantly associated with the reduced serotonin uptake and secretion characteristic of storage pool deficiency.This publication has 4 references indexed in Scilit:
- ULTRASTRUCTURE OF RESTING AND ACTIVATED STORAGE POOL DEFICIENT PLATELETS FROM ANIMALS WITH THE CHEDIAK-HIGASHI-SYNDROME1982
- HETEROGENEITY IN STORAGE POOL DEFICIENCY - STUDIES ON GRANULE-BOUND SUBSTANCES IN 18 PATIENTS INCLUDING VARIANTS DEFICIENT IN ALPHA-GRANULES, PLATELET FACTOR 4, BETA-THROMBOGLOBULIN, AND PLATELET-DERIVED GROWTH-FACTOR1979
- Altered uptake and release of 14C-serotonin in platelets following incubation of platelet-rich plasma with EDTAThrombosis Research, 1979
- FOCAL GLOMERULAR SCLEROSIS IN FAWN-HOODED RAT1978