Effect of O6-benzylguanine on the sensitivity of human colon tumor xenografts to 1,3-BIS(2-chloroethyl)-1-nitrosourea(BCNU)
- 20 July 1993
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 46 (2) , 285-290
- https://doi.org/10.1016/0006-2952(93)90416-t
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Modulation of nitrosourea resistance in human colon cancer by O6-methylguanineBiochemical Pharmacology, 1992
- Phase I Study of Streptozocin- and Carmustine-Sequenced Administration in Patients With Advanced CancerJNCI Journal of the National Cancer Institute, 1992
- DNA alkylation by the haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990
- Modulation of Mammalian O6-Alkylguanine-DNA Alkyltransferase in vivo by O6-Benzylguanine and its Effect on the Sensitivity of a Human Glioma Tumor to l-(2-chloroethyl)-3-(4-methylcyclohexyl)-l-nitrosoureaCancer Communications, 1990
- Inhibition of a Specific DNA Repair System and Nitrosourea Cytotoxicity in Resistant Human Cancer CellsCancer Communications, 1989
- Formation of covalent complexes between humanO6alkyltransferase and BCNU-treated defined length synthetic oligodeoxynucleotidesNucleic Acids Research, 1988
- Properties and assay of mammalian O6-alkyguanine-DNA alkyltransferasePharmacology & Therapeutics, 1987
- Isolation and purification of O6-Alkylguanine-DNA alkyltransferase from human leukemic cells. Prevention of chloroethylnitrosourea-induced cross-links by purified enzymePharmacology & Therapeutics, 1985
- Adjuvant Therapy of Colon Cancer — Results of a Prospectively Randomized TrialNew England Journal of Medicine, 1984
- Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferaseNucleic Acids Research, 1983