The Questionable Relation between Cochlear Pigmentation and Noise-Induced Hearing Loss
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in International Journal of Audiology
- Vol. 24 (4) , 260-268
- https://doi.org/10.3109/00206098509070110
Abstract
Some evidence has suggested that susceptibility to noise-induced hearing loss may be inversely proportional to the amount of melanin in the cochlea. However, published data have not been consistent in demonstrating this relation, and some results may be contaminated by lack of genetic control in experimental animals. In this investigation, noise-induced hearing loss was evaluated in pigmented and albino C57BL/6J mice that differed only in their ability to produce melanin. Surface-recorded electric responses to sound were used to assess auditory sensitivity. Results indicated no difference between the two groups either in pre-exposure thresholds or in magnitude of noise-induced threshold shift. Relation éventuelle entre pigmentation cochléaire et surdité due au bruit Quelques recherches ont suggéré que la prédisposition à la réduction de sensibilité auditive provoquée par le bruit pourrait ětre inversement proportionnelle à la quantité de mélanine dans 'organe cochléaire. Cependant, les données publiées 'ont pas démontré cette relation 'une façon consistente, et il semble que certains résultats aient été contaminés par 'absence de contrôle génétique chez les animaux de laboratoire. Dans cette recherche, on a mesuré la réduction de sensibilité auditive provoquée par le bruit chez des souris albinos et pigmentées différant dans leur aptitude à produire de la mélanine. Pour établir la sensibilité auditive, on a utilisé 'enregistrement des potentiels évoqués auditifs en surface. Les résultats 'ont indiqué aucune différence entre les deux groupes, ni dans les seuils de pré-exposition ni dans Pimportance de la surdité induite par le bruit.Keywords
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