T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication
- 1 October 1979
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 281 (5731) , 456-461
- https://doi.org/10.1038/281456a0
Abstract
A novel ATP-dependent DNA topoisomerase which makes reversible double-strand breaks in the DNA double helix has been purified to near homogeneity from T4 bacteriophage-infected Escherichia coli cells. Genetic data suggest that this activity is essential for initiating T4 DNA replication forks in vivo.This publication has 34 references indexed in Scilit:
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