Sympathetic Nerve Stimulation and Vascular Resistance in a Pump-Perfused Dog Lung Lobe

Abstract
The pump-perfused in situ left lower lobe of the dog lung responded to electrical stimulation of the stellate ganglion by increasing vascular resistance. A dose of phentolamine, which blocked the vasoconstrictor response to infused norepinephrine but not hypoxia, blocked the response to stellate ganglion stimulation. Sympathetic stimulation had relatively little influence on lobar blood volume, but appeared to decrease total lobar vascular compliance.