Kinetics of Hepatocyte Spheroid Formation
- 5 September 1994
- journal article
- Published by Wiley in Biotechnology Progress
- Vol. 10 (5) , 460-466
- https://doi.org/10.1021/bp00029a002
Abstract
Cultured hepatocytes have been explored for use in a bioartificial liver. Spheroids formed by cultured hepatocytes exhibit enhanced liver‐specific functions. The kinetics of spheroid formation, using...Keywords
This publication has 15 references indexed in Scilit:
- Tissue EngineeringScience, 1993
- Development of a Hybrid Bioartificial LiverAnnals of Surgery, 1993
- Evaluation of a hepatocyte‐entrapment hollow fiber bioreactor: A potential bioartificial liverBiotechnology & Bioengineering, 1993
- Cultivation of mammalian cells as aggregates in bioreactors: Effect of calcium concentration of spatial distribution of viabilityBiotechnology & Bioengineering, 1993
- Long-term culture of rat liver cell spheroids in hormonally defined mediaExperimental Cell Research, 1990
- Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environmentsExperimental Cell Research, 1990
- Continued high albumin production by multicellular spheroids of adult rat hepatocytes formed in the presence of liver-derived proteoglycansBiochemical and Biophysical Research Communications, 1989
- Hepatocyte cell surface polarity as demonstrated by lectin binding.Journal of Histochemistry & Cytochemistry, 1988
- Experimental Artificial Liver Support with Emphasis on Fulminant Hepatic Failure: Concepts and ReviewSeminars in Liver Disease, 1986
- Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities.The Journal of cell biology, 1985