The biochemical effect of auromomycin on bacterial cells.
- 1 January 1979
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 32 (7) , 706-710
- https://doi.org/10.7164/antibiotics.32.706
Abstract
The mechanism of action of auromomycin was studied with intact cells of Bacillus subtilis. The antibiotic exhibited a preferential inhibition of DNA synthesis over RNA and protein syntheses. The strand scission of cellular DNA was induced by the drug, and DNA was degraded into acid-soluble fragments. The results suggested that DNA is the chemoreceptor of auromomycin.This publication has 2 references indexed in Scilit:
- DNA STRAND SCISSION INVIVO AND INVITRO BY AUROMOMYCIN1979
- Studies on auromomycin.The Journal of Antibiotics, 1979