THE EFFECT OF RELAXIN ON UTERINE PHOSPHORYLASE IN THE RAT1
- 1 November 1960
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 67 (5) , 663-667
- https://doi.org/10.1210/endo-67-5-663
Abstract
An injection of relaxin into estrogen-primed, spayed rats increases uterine phosphorylase a activity per unit weight of tissue. Similar results were obtained when estrogen was substituted for relaxin. The estrogen-priming requirement for the effect of relaxin, in this particular instance on uterine glycogen, was not met by priming with testosterone. In the spayed non-primed rat, relaxin increased total phosphorylase activity in the entire uterus as well as increasing the uterine weight. Over-all, relaxin and estrogen are very similar in their effects on phosphorylase activity.Keywords
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