INTERLEUKIN-2 PRODUCTION AND RESPONSE TO EXOGENOUS INTERLEUKIN-2 IN A PATIENT WITH THE ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS)

  • 1 January 1984
    • journal article
    • research article
    • Vol. 56  (1) , 14-17
Abstract
The ability of lymphocytes from a patient suffering from the acquired immune deficiency syndrome (AIDS) to produce interleukin-2 (IL-2) was comparable to that of his healthy sex partner and to that of a normal control. Addition of exogenous IL-2 to lymphocyte cultures did not improve the poor mitogen response to phytohemagglutinin in this patient. The underlying defect in this AIDS patient is possibly due to an IL-2 receptor defect.