Serial passages of larvalEchinococcus granulosus from equine origin in mice

Abstract
Sterile secondaryE. granulosus cysts≦1 mm in diameter, collected from mice 6–13 months after experimental infection were transferred to helminth-free mice. They developed into larger cysts showing fertility and daughter cyst formation at autopsy 9–14 months p.i. Average growth of the largest cyst per mouse, expressed in log volume (μl), amounted to 0.30±0.03 per month; average growth of all cysts per mouse, expressed in log weight (mg) amounted to 0.27±0.02 per month. An inversed ratio was found between total parasite weight and number of cysts injected. The practical importance of these observations is discussed.

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